منابع مشابه
New Horizons for Plant Translational Research
1 PLOS Biology, Public Library of Science, Cambridge, United Kingdom, 2 Howard Hughes Medical Institute, University of North Carolina, Chapel Hill, North Carolina, United States of America, 3 Department of Biology, University of North Carolina, Chapel Hill, North Carolina, United States of America, 4 The Sainsbury Laboratory, Norwich, United Kingdom, 5 Department of Plant Breeding and Genetics,...
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In an era of high-throughput "omic" technologies, the unprecedented amount of data that can be generated presents a significant opportunity but simultaneously an even greater challenge for oncologists trying to provide personalized treatment. Classically, preclinical testing of new targets and identification of active compounds against those targets have entailed the extensive use of establishe...
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Over the last decade, comprehensive genome-wide sequencing studies have enabled us to find out unexpected genetic alterations of metabolism in cancer. An example is the identification of arginine missense mutations of isocitrate dehydrogenases-1 and -2 (IDH1/2) in glioma, acute myeloid leukemia (AML), chondrosarcomas, and cholangiocarcinoma. These alterations are closely associated with the pro...
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Echinocandins are N-acyl-substituted cyclic hexapeptides with potent in vitro and in vivo activity against Candida species that are used for primary treatment and prevention of candidemia and invasive candidiasis. Recent progress in the translational research of echinocandins has led to new approaches for treatment of central venous catheter Candida biofilms. Other studies have laid the experim...
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PURPOSE Clinical microsurgery has been introduced in many fields, while experimental microsurgery has the cross-disciplinary features of the sciences and techniques for growth of medicine, pharmacology, veterinary, engineering etc. Training protocol, proposing a new name as Translational Microsurgery, was introduced. METHODS Reconstructive skills of hepatic artery in pediatric living donor li...
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ژورنال
عنوان ژورنال: The Lancet Respiratory Medicine
سال: 2014
ISSN: 2213-2600
DOI: 10.1016/s2213-2600(14)70150-x